Cowles S R, Loh K K
South Med J. 1977 Jun;70(6):694-7. doi: 10.1097/00007611-197706000-00017.
To evaluate the usefulness of percutaneous needle liver biopsy in the initial staging of lymphoma patients, 115 patients presenting to M. D. Anderson Hospital between Sept 1, 1972, and Aug 31, 1975, and having either percutaneous (45) or celiotomy (70) liver biopsy were identified. Sixty-six patients had Hodgkin's disease, 49 non-Hodgkin's lymphoma. Overall, results of 13 biopsies were positive--six by percutaneous biopsy, seven by celiotomy. Results showed little difference in yield between percutaneous and celiotomy biopsy. Positivity increased with increasing clinical stage, increasing age (Hodgkin's patients), and increasing number of abnormal liver function tests. It is concluded that percutaneous liver biopsy is useful in lymphoma staging, especially in patients with at least one abnormal liver function test, and in patients with Hodgkin's disease, mixed cell type. The early identification of otherwise unrecognized stage IV disease can spare many patients the morbidity of staging celiotomy.
为评估经皮肝穿刺活检在淋巴瘤患者初始分期中的作用，我们确定了1972年9月1日至1975年8月31日期间在MD安德森医院就诊、接受过经皮肝穿刺活检（45例）或剖腹肝活检（70例）的115例患者。其中66例患有霍奇金病，49例患有非霍奇金淋巴瘤。总体而言，13例活检结果呈阳性，经皮肝穿刺活检阳性6例，剖腹肝活检阳性7例。结果显示，经皮肝穿刺活检和剖腹肝活检的阳性率差异不大。阳性率随着临床分期的增加、年龄的增长（霍奇金病患者）以及肝功能异常检查次数的增加而升高。得出的结论是，经皮肝穿刺活检在淋巴瘤分期中有用，尤其是在至少有一项肝功能异常检查的患者以及混合细胞型霍奇金病患者中。早期识别原本未被发现的IV期疾病可以使许多患者避免剖腹分期带来的并发症。
