Stefanadis C, Toutouzas K, Vlachopoulos C, Tsiamis E, Kallikazaros I, Stratos C, Vavuranakis M, Toutouzas P
Department of Cardiology, Hippokration Hospital, University of Athens, Greece.
Cathet Cardiovasc Diagn. 1996 Jun;38(2):159-70. doi: 10.1002/(SICI)1097-0304(199606)38:2<159::AID-CCD8>3.0.CO;2-8.
Acute or subacute thrombosis and late restenosis remain the main limitations of permanent stenting. In an effort to address these limitations, an autologous vein graft-coated stent (AVGCS) was developed at our institution. This stent consists of a conventional stent (Palmaz or Palmaz-Schatz, Johnson and Johnson), which is covered by an autologous vein graft. After successful experimental implantation, we report here the immediate results of the percutaneous implantation of AVGCS in 7 patients with coronary artery disease (6 de novo lesions and 1 bailout case). The results of this preliminary study indicate that the preparation of the AVGCS is easy and feasible. The implantation of the AVGCS was uncomplicated, and the immediate angiographic results were excellent. This new type of coated stent may be useful in addressing current limitations of balloon angioplasty.
急性或亚急性血栓形成以及晚期再狭窄仍然是永久性支架置入术的主要局限性。为了解决这些局限性，我们机构研发了一种自体静脉移植涂层支架（AVGCS）。这种支架由一个传统支架（Palmaz或Palmaz-Schatz，强生公司）组成，表面覆盖有自体静脉移植物。在成功进行实验性植入后，我们在此报告7例冠心病患者（6例初发病变和1例补救病例）经皮植入AVGCS的即时结果。这项初步研究的结果表明，AVGCS的制备简便可行。AVGCS的植入过程并不复杂，即时血管造影结果极佳。这种新型涂层支架可能有助于解决当前球囊血管成形术的局限性。
