Sakuramoto C, Kanai I, Matoba M, Asato F, Goto F
Department of Anesthesia, Toshiba-Rinkan Hospital, Kanagawa, Japan.
Clin J Pain. 1996 Jun;12(2):142-4. doi: 10.1097/00002508-199606000-00010.
Thoracic epidural morphine was administered to five patients who underwent radical resection and reconstructive surgery for oral malignant tumors.
In case 1, an epidural catheter was inserted at the T3-T4 interspace, and 4 mg morphine was administered through the catheter approximately 5 h before the end of surgery. Forty-five minutes after the end of surgery, a total of 10 mg morphine was continuously infused over a 2-day period using a balloon infusion system. The patient did not complain of pain, and no other analgesics were necessary. There were no serious side effects throughout the treatment of postoperative pain. Good control of pain was obtained by this method in four similar cases.
Thoracic epidural morphine was effective in the relief of postoperative pain following oral surgery in five cases.
对5例行口腔恶性肿瘤根治性切除及重建手术的患者给予胸段硬膜外吗啡。
病例1中，于T3 - T4间隙置入硬膜外导管，在手术结束前约5小时经导管给予4毫克吗啡。术后45分钟，使用球囊输注系统在2天内持续输注共计10毫克吗啡。患者未诉疼痛，无需使用其他镇痛药。在整个术后疼痛治疗过程中未出现严重副作用。通过该方法在另外4例类似病例中也获得了良好的疼痛控制。
胸段硬膜外吗啡对5例口腔手术后的术后疼痛缓解有效。
