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两种给药方式对β2 激动剂支气管扩张作用的比较

[A comparison of two delivery methods on the bronchodilator effects of beta 2-stimulant].

作者信息

Kishida M, Suzuki I, Koshibu T, Matsumoto H, Uchiyama Y, Kabayama H, Nagayama T, Sasamoto A, Aoki T

机构信息

Second Department of Pediatrics, Toho University School of Medicine, Japan.

出版信息

Arerugi. 1996 Jun;45(6):542-5.

PMID:8776948
Abstract

The airway response to a bronchodilator, salbutamol delivered by a new handy ultrasonic nebulizer and the compressed air nebulizer was studied in a blind manner. Patients by the ultrasonic nebulizer had better percent increase in FVC and FEV1 significantly and in other parameters showed a tendency to being better than those by the compressed air nebulizer. These results suggest that this ultrasonic nebulizer may be more useful than the compressed air nebulizer as inhalation therapy for bronchial asthma. This ultrasonic nebulizer has several advantages over the compressed air nebulizer. This nebulizer is compact size, light weight and has dry batteries as power source, making it more convenient for travel and use at workplace.

摘要

以盲法研究了新型便捷超声雾化器和压缩空气雾化器输送支气管扩张剂沙丁胺醇时的气道反应。使用超声雾化器的患者的用力肺活量(FVC)和第一秒用力呼气容积(FEV1)的百分比增加明显更好,并且在其他参数方面显示出比使用压缩空气雾化器的患者更好的趋势。这些结果表明,作为支气管哮喘的吸入疗法,这种超声雾化器可能比压缩空气雾化器更有用。这种超声雾化器相对于压缩空气雾化器有几个优点。该雾化器尺寸紧凑、重量轻且以干电池作为电源,使其在旅行和工作场所使用更加方便。

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