Ishiura Y, Fujimura M, Minami S, Ueda A, Iwata M, Watanabe K, Shinagawa T, Yasui M, Matsuda T, Kitagawa M
Department of Internal Medicine, Inami General Hospital, Toyama, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1996 Mar;34(3):317-21.
A 75-year-old man with multiple myeloma presented with fever and respiratory symptoms. A chest roentgenogram showed interstitial shadows and transbronchial lung biopsy revealed diffuse infiltration of amyloid in the alveolar walls. Analysis of bronchoalveolar lavage fluid showed the presence of an IgA-lambda paraprotein, and the IgA/albumin ratio was similar to that in serum. However, plasma cells could not be detected in the cells obtained by lavage. We know of no previous case in Japan in which bronchoalveolar lavage fluid was examined in a case of diffuse alveolar septal amyloidosis.
一名75岁的多发性骨髓瘤男性患者出现发热和呼吸道症状。胸部X线片显示间质阴影，经支气管肺活检显示肺泡壁有淀粉样蛋白弥漫性浸润。支气管肺泡灌洗 fluid分析显示存在IgA-λ副蛋白，且IgA/白蛋白比值与血清中的相似。然而，在灌洗获得的细胞中未检测到浆细胞。我们所知，在日本此前尚无在弥漫性肺泡间隔淀粉样变性病例中检查支气管肺泡灌洗 fluid的案例。
