Samsonov V A, Andreeva R M, Fedorova L A, Nekachalov V V
Ter Arkh. 1995;67(10):53-5.
Autopsy records have been analysed for 52 fatal cases of extrahepatic bile ducts cancer. Primary cancer most frequently involved common bile duct (37 cases). Histologically, skirr was found in 1 case, small-cell cancer in 1 case, adenocarcinoma in 50 cases. Radical and palliative surgery was performed in 4 and 24 cases, respectively. The invasion into the adjacent tissues and organs occurred in 34.6%, metastases were found in 32.7% of cases. Another primary lesion arose in 2 patients (sigmoid, thyroid cancer). 92.3% of patients developed jaundice with hepatic or hepatorenal insufficiency. Purulent hepatic disorder, impairment of intrahepatic bile ducts were seen in 40.4%. Focal pneumonia emerged in 32.7% of patients. Accurate lifetime diagnosis was made in 30 of 52 patients only.
对52例肝外胆管癌死亡病例的尸检记录进行了分析。原发性癌最常累及胆总管(37例)。组织学上,1例为硬癌,1例为小细胞癌,50例为腺癌。分别有4例和24例患者接受了根治性手术和姑息性手术。34.6%的病例发生了对邻近组织和器官的侵犯,32.7%的病例发现有转移。2例患者出现了另一种原发性病变(乙状结肠癌、甲状腺癌)。92.3%的患者出现黄疸并伴有肝或肝肾不全。40.4%的患者出现化脓性肝病、肝内胆管损害。32.7%的患者出现局灶性肺炎。52例患者中只有30例得到了准确的生前诊断。