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[肝外胆管癌的临床形态学特征(52例尸检病例分析)]

[The clinico-morphological characteristics of cancer of the extrahepatic bile ducts (an analysis of 52 autopsy cases)].

作者信息

Samsonov V A, Andreeva R M, Fedorova L A, Nekachalov V V

出版信息

Ter Arkh. 1995;67(10):53-5.

PMID:8779108
Abstract

Autopsy records have been analysed for 52 fatal cases of extrahepatic bile ducts cancer. Primary cancer most frequently involved common bile duct (37 cases). Histologically, skirr was found in 1 case, small-cell cancer in 1 case, adenocarcinoma in 50 cases. Radical and palliative surgery was performed in 4 and 24 cases, respectively. The invasion into the adjacent tissues and organs occurred in 34.6%, metastases were found in 32.7% of cases. Another primary lesion arose in 2 patients (sigmoid, thyroid cancer). 92.3% of patients developed jaundice with hepatic or hepatorenal insufficiency. Purulent hepatic disorder, impairment of intrahepatic bile ducts were seen in 40.4%. Focal pneumonia emerged in 32.7% of patients. Accurate lifetime diagnosis was made in 30 of 52 patients only.

摘要

对52例肝外胆管癌死亡病例的尸检记录进行了分析。原发性癌最常累及胆总管(37例)。组织学上,1例为硬癌,1例为小细胞癌,50例为腺癌。分别有4例和24例患者接受了根治性手术和姑息性手术。34.6%的病例发生了对邻近组织和器官的侵犯,32.7%的病例发现有转移。2例患者出现了另一种原发性病变(乙状结肠癌、甲状腺癌)。92.3%的患者出现黄疸并伴有肝或肝肾不全。40.4%的患者出现化脓性肝病、肝内胆管损害。32.7%的患者出现局灶性肺炎。52例患者中只有30例得到了准确的生前诊断。

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