Nehal K S, Levine V J, Ashinoff R
Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, USA.
Dermatol Surg. 1996 Aug;22(8):683-6. doi: 10.1111/j.1524-4725.1996.tb00617.x.
The Q-switched ruby laser (QSRL) is useful in the treatment of benign pigmented lesions and tattoos. Two spot sizes are available in the QSRL (5 and 6.5 mm). It has not been shown if one spot size is more efficacious in the treatment of benign pigmented lesions and tattoos.
The purpose of this study is to compare the clinical lightening and side effects observed with the 5.0- and 6.5-mm spot sizes of the QSRL in the treatment of benign pigmented lesions and tattoos.
Eleven patients with 12 benign pigmented lesions or tattoos were prospectively studied with the QSRL. Half of the lesion was treated with the 5.0-mm spot size while the other half was treated with the 6.5-mm spot size. Clinical lightening of the lesion was assessed using pretreatment and posttreatment photographs.
No significant clinical difference in the lightening of lesions or in the side effect profile was observed with either spot size.
The 5.0- and 6.5-mm spot sizes of the QSRL are equally efficacious in the removal of benign pigmented lesions and tattoos. It seems prudent to use the 6.5-mm spot size when treating large lesions to reduce treatment time, patient discomfort, and treatment cost.
调Q红宝石激光（QSRL）可用于治疗良性色素沉着病变和纹身。QSRL有两种光斑尺寸（5毫米和6.5毫米）。目前尚未表明哪种光斑尺寸在治疗良性色素沉着病变和纹身上更有效。
本研究的目的是比较QSRL的5.0毫米和6.5毫米光斑尺寸在治疗良性色素沉着病变和纹身上观察到的临床色素减退情况和副作用。
对11例患有12处良性色素沉着病变或纹身的患者使用QSRL进行前瞻性研究。病变的一半用5.0毫米光斑尺寸治疗，另一半用6.5毫米光斑尺寸治疗。使用治疗前和治疗后的照片评估病变的临床色素减退情况。
两种光斑尺寸在病变色素减退或副作用方面均未观察到显著临床差异。
QSRL的5.0毫米和6.5毫米光斑尺寸在去除良性色素沉着病变和纹身上同样有效。在治疗大面积病变时，使用6.5毫米光斑尺寸以减少治疗时间、患者不适和治疗成本似乎是明智的。
