Burke B J, Savage P E, Sherriff R J, Dixon H G
Lancet. 1979 Jun 30;1(8131):1372-3. doi: 10.1016/s0140-6736(79)92009-9.
A diabetic mother produced twins dissimilar in both appearance and blood biochemistry--one being clearly macrosomic and "hyperinsulinised" at delivery, the other apparently normal. It is suggested that the development of fetal hyperinsulinism may depend not only on maternal blood-glucose control but also on fetal blood-supply or genetic factors.
一位患有糖尿病的母亲生下了一对外貌和血液生化指标都不相同的双胞胎——其中一个在出生时明显巨大且“高胰岛素化”,另一个看起来正常。有人提出,胎儿高胰岛素血症的发展可能不仅取决于母亲的血糖控制,还取决于胎儿的血液供应或遗传因素。