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[血液病中生成与破坏的红细胞的定量变化]

[Quantitative changes in produced and destroyed erythrocytes in hemopathy].

作者信息

Avramova D, Karakostov K, Dimitrov L

出版信息

Vutr Boles. 1977;16(2):51-8.

PMID:878447
Abstract

Ten healthy volunteers and 38 patients with iron deficiency anemia, aplastic anemia, chronic lymphadenosis, myelofibrosis were examined. On the base of the results from the kinetics of iron-59 and the marked with chromium-51 erythrocytes and from the corrected per cent reticulocytes, the authors set up the task to evaluate the etythropoetic potentialities of bone marrow and the severity of erythrocyte balance disorder, studying the quantity of produced and destroyed erythrocytes daily and comparing the data obtained with those from aspiration biopsy and treparobiopsy. The results, obtained by the authors, reveal the high potentialities indicated by the isotope investigation with iron-59 and chromium-51 as well as the corrected per cent of reticulocytes, for the evaluation of the erythropoetic potentialities of bone marrow and the high correlation between the results obtained and the clinical picture.

摘要

对10名健康志愿者以及38名患有缺铁性贫血、再生障碍性贫血、慢性淋巴结病、骨髓纤维化的患者进行了检查。根据铁-59动力学、铬-51标记红细胞以及校正网织红细胞百分比的结果,作者设定任务,通过每日研究产生和破坏的红细胞数量,并将所得数据与穿刺活检和环钻活检的数据进行比较,来评估骨髓的红细胞生成潜力以及红细胞平衡紊乱的严重程度。作者获得的结果表明,使用铁-59和铬-51进行同位素研究以及校正网织红细胞百分比,对于评估骨髓的红细胞生成潜力具有很高的潜力,并且所得结果与临床表现之间具有高度相关性。

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