Wharton J T, Tortolero-Luna G, Linares A C, Malpica A, Baker V V, Cook E, Johnson E, Follen Mitchell M
Department of Gynecologic Oncology, University of Texas M.D. Anderson Cancer Center, Houston, USA.
Obstet Gynecol Clin North Am. 1996 Jun;23(2):325-45.
Vaginal cancer is infrequent, but the morbidity associated with treatment is high. Delays in diagnosis account for presentations in advanced stages. Screening is probably not warranted given the low incidence, but inspection of the vagina should be performed at the time of Pap smear screening. No molecular markers are currently promising. Chemoprevention with retinoids may be feasible.
阴道癌并不常见,但治疗相关的发病率很高。诊断延迟导致患者在晚期才就诊。鉴于发病率较低,可能无需进行筛查,但在巴氏涂片筛查时应检查阴道。目前尚无有前景的分子标志物。使用维甲酸进行化学预防可能可行。