Haerten K, Both A, Lück J, Herzer J, Loogen F
Z Kardiol. 1977 May;66(5):242-6.
After mitral valve replacement hemodynamic abnormalities persist. These abnormalities were studied 1 year postoperatively. In 50 randomized patients; 15 with Starr-Edwards (SEM), 15 with Lillehei-Kaster (LKM) and 20 with Björk-Shiley (BSM) prostheses at rest and during exercise. Simultaneously were determined: pulmonary arterial pressure, left atrial pressure, left ventricular enddiastolic pressure, mean diastolic pressure gradient across the prostheses, cardiac index, stroke volume index, valve orifice area, and ejection fraction. The results show an important stenosis by the prostheses leading to high pressure increase in pulmonary artery and left atrium during excercise. This stenosis depends on valve size and type. Björk-Shiley tilting disc valves show the best hemodynamic results. This may be due to the most favourable ratio between internal and external diameter. Starr-Edwards prostheses with identical sizes show the most identical results if compared to each other. Therfore we suggest that Starr-Edwards prostheses open completely in every case. However, there is an important pressure gradient caused by the small internal diameter. Lillehei-Kaster pivoting disc valves reach surprisingly small functional valve areas. This may be caused by an incomplete opening of the disc.
二尖瓣置换术后血流动力学异常持续存在。对这些异常情况在术后1年进行了研究。在50例随机分组的患者中,15例植入斯塔尔-爱德华兹(SEM)人工瓣膜,15例植入利勒黑-卡斯特(LKM)人工瓣膜,20例植入比约克-希利(BSM)人工瓣膜,分别在静息和运动状态下进行研究。同时测定了肺动脉压、左心房压、左心室舒张末期压、人工瓣膜两端的平均舒张压梯度、心脏指数、每搏量指数、瓣膜开口面积和射血分数。结果显示,人工瓣膜导致明显狭窄,在运动时引起肺动脉和左心房压力显著升高。这种狭窄取决于瓣膜大小和类型。比约克-希利倾斜碟瓣显示出最佳的血流动力学结果。这可能是由于其内外径比例最为有利。相同尺寸的斯塔尔-爱德华兹人工瓣膜相互比较时显示出最为相似的结果。因此我们建议,斯塔尔-爱德华兹人工瓣膜在每种情况下都能完全打开。然而,由于内径较小会导致明显的压力梯度。利勒黑-卡斯特旋转碟瓣的功能性瓣膜面积小得出奇。这可能是由于碟片未完全打开所致。