Varshaver N B
Mol Gen Mikrobiol Virusol. 1996 Jan-Mar(1):3-10.
The review presents data on the history of the discovery of tumor suppressor genes (antioncogenes) and the new data on their mapping and cloning. Special attention is given to the mechanisms of retinoblastoma and p53 gene action, their role in the regulation of cell proliferation and malignant growth inhibition.
这篇综述介绍了肿瘤抑制基因(抗癌基因)发现史的数据,以及它们定位和克隆的新数据。特别关注视网膜母细胞瘤和p53基因的作用机制,它们在细胞增殖调控和抑制恶性生长中的作用。