Sammut E B, Kannegieter N J
Department of Veterinary Clinical Sciences, University of Sydney, New South Wales.
Aust Vet J. 1995 Jan;72(1):25-8. doi: 10.1111/j.1751-0813.1995.tb03471.x.
Intra-articular injection of sodium monoiodoacetate (MIA) was investigated as an agent for chemical arthrodesis of the distal hock joints in the horse. Five horses diagnosed with either spavin (three horses), a small tarsal bone fracture or a failed surgical arthrodesis, had 150 mg of MIA injected into the tarsometatarsal (TMT) joint of the affected hock(s). Eight joints were treated in the five horses. Follow-up evaluation by clinical and radiological examination took place over 9 to 14 months. Two of the five horses were sound at the conclusion of the study and one horse, although lame after flexion, was considered by the owner to have been treated successfully. One of eight TMT joints showed complete radiographic fusion. Complications after treatment included pain, chronic lameness and swelling. It was concluded that chemical arthrodesis using this technique can not be recommended as being a superior treatment as compared with surgical arthrodesis at this time but is deserving of further clinical evaluation.
研究了关节内注射单碘乙酸钠(MIA)作为马跗关节远端化学融合剂的作用。五匹马被诊断患有跗关节病(三匹马)、跗骨小骨折或手术关节融合失败,将150毫克MIA注射到受影响跗关节的跗跖关节(TMT)中。五匹马的八个关节接受了治疗。通过临床和放射学检查进行了9至14个月的随访评估。研究结束时,五匹马中有两匹恢复健康,一匹马虽然屈曲后跛行,但主人认为治疗成功。八个TMT关节中有一个显示出完全的影像学融合。治疗后的并发症包括疼痛、慢性跛行和肿胀。结论是,与手术关节融合相比,目前不能推荐使用这种技术进行化学关节融合作为一种更优的治疗方法,但值得进一步的临床评估。