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重症监护患者年龄与“不要复苏”医嘱使用之间的关系。年龄歧视的证据。

The relationship between age and the use of DNR orders in critical care patients. Evidence for age discrimination.

作者信息

Boyd K, Teres D, Rapoport J, Lemeshow S

机构信息

Department of Medicine, Baystate Medical Center, Springfield, Ill., USA.

出版信息

Arch Intern Med. 1996 Sep 9;156(16):1821-6.

PMID:8790076
Abstract

OBJECTIVE

To determine whether a relationship exists between the use of do-not-resuscitate (DNR) orders in the intensive care unit and the age of the patient after controlling for the severity of illness.

METHODS

Patients from the Mortality Probability Model database, which includes 6103 patients in 4 large hospitals, and from a second database, which includes 3226 additional patients in 25 hospitals, were analyzed through logistic regression seeking a relationship between age and DNR use. Adult medical and surgical intensive care units from 27 hospitals in the United States were included.

RESULTS

In the Mortality Probability Model database, 11.4% of the patients had DNR orders written. In the group of patients younger than 65 years, 8% had DNR orders. This percentage climbed rapidly with age. For age ranges of 65 to younger than 75 years, 75 to younger than 85 years, and 85 years or older, the percentage of patients who had a DNR order was 11.2%, 18.9%, and 32.6%, respectively. Similar results were found in the second database: 5.4% of patients had DNR orders and, again, the rise in the use of DNR orders was associated with increased age. For patients younger than 75 years, 4.2% had DNR orders. For the older groups, 75 to younger than 85 years and 85 years and older, the rates were 8.8% and 15.4%, respectively. Logistic regression was used to control for severity of illness; when compared with patients younger than 65 years, patients 75 to younger than 85 years were 50% more likely to have DNR orders written and patients 85 years or older were 140% more likely to have DNR orders written.

CONCLUSIONS

Older patients (> or = 75 years old) are significantly more likely than younger patients to have DNR orders written even after the severity of illness is controlled as a confounding variable. This association suggests age discrimination and becomes stronger as patient age increases.

摘要

目的

在控制疾病严重程度后,确定重症监护病房中“不要复苏”(DNR)医嘱的使用与患者年龄之间是否存在关联。

方法

通过逻辑回归分析来自死亡率概率模型数据库(包括4家大型医院的6103例患者)以及另一个数据库(包括25家医院的3226例额外患者)的患者,以寻找年龄与DNR医嘱使用之间的关系。纳入了美国27家医院的成人内科和外科重症监护病房的患者。

结果

在死亡率概率模型数据库中,11.4%的患者有DNR医嘱记录。在65岁以下的患者组中,8%有DNR医嘱。这一比例随年龄迅速上升。对于65至75岁以下、75至85岁以下以及85岁及以上的年龄范围,有DNR医嘱的患者比例分别为11.2%、18.9%和32.6%。在第二个数据库中也发现了类似结果:5.4%的患者有DNR医嘱,同样,DNR医嘱使用的增加与年龄增长相关。对于75岁以下的患者,4.2%有DNR医嘱。对于年龄较大的组,75至85岁以下以及85岁及以上,比例分别为8.8%和15.4%。使用逻辑回归控制疾病严重程度;与65岁以下的患者相比,75至85岁以下的患者有DNR医嘱记录的可能性高50%,85岁及以上的患者有DNR医嘱记录的可能性高140%。

结论

即使将疾病严重程度作为混杂变量进行控制,老年患者(≥75岁)比年轻患者更有可能有DNR医嘱记录。这种关联表明存在年龄歧视,并且随着患者年龄的增加而变得更强。

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