Glaser C, Pruckmayer M, Staudenherz A, Rasse M, Lang S, Leitha T
University Clinic of Maxillofacial Surgery, Vienna, Austria.
J Nucl Med. 1996 Sep;37(9):1526-8.
We report the staging results and the surgical outcome of a male patient with squamous-cell carcinoma in the floor of the mouth and a bone SPECT scan suggestive of local tumor infiltration of the mandible. Additional 99mTc-sestamibi SPECT imaging of the primary tumor and superimposing of both studies excluded osseous tumor spread and less extensive surgery was performed. Pathohistological examination confirmed the scintigraphic results and indicated a nonspecific periostal reaction as the cause of the positive bone scan. Nevertheless, a high-resolution camera and careful superimposition of both studies is mandatory if the differential diagnosis of an osseous tumor spread of a malignant tumor in the floor of the mouth and possibly less extensive surgery is at stake.
我们报告了一名男性口腔底部鳞状细胞癌患者的分期结果及手术结果，该患者的骨SPECT扫描提示下颌骨存在局部肿瘤浸润。对原发肿瘤进行的额外99m锝-甲氧基异丁基异腈（99mTc-sestamibi）SPECT成像以及两项研究结果的叠加排除了骨肿瘤扩散，因此实施了范围较小的手术。病理组织学检查证实了闪烁扫描结果，并表明骨扫描阳性的原因是一种非特异性骨膜反应。然而，如果涉及口腔底部恶性肿瘤骨肿瘤扩散的鉴别诊断以及可能实施范围较小的手术时，必须使用高分辨率相机并仔细叠加两项研究结果。
