Felner J M, Harwood S, Mond H, Plauth W, Brinsfield D, Schlant R C
Am J Cardiol. 1977 Aug;40(2):206-11. doi: 10.1016/0002-9149(77)90010-8.
Three children with loud systolic honks were studied noninvasively with phonocardiography and echocardiography. It was shown that the precordial honk, like the late systolic mitral murmur and the clicking apical systolic sound, is part of a continuum of auscultatory sounds that result from a defect of mitral valve support and are classified under the general heading of mitral valve prolapse syndrome. Prolapse of one or both of the mitral valve leaflets is believed to cause the characteristic auscultatory findings of click, murmur or honk. The timing of these sounds in systole varies with different physiologic or pharmacologic maneuvers. Variations in the onset of prolapse are associated with changes in left ventricular end-diastolic dimensions.
对三名伴有响亮收缩期喀喇音的儿童进行了心音图和超声心动图的无创检查。结果显示,心前区喀喇音与收缩晚期二尖瓣杂音及心尖收缩期喀喇音一样,是由二尖瓣支持结构缺陷导致的一系列听诊音的一部分,归类于二尖瓣脱垂综合征这一总体范畴。二尖瓣一个或两个瓣叶的脱垂被认为会导致喀喇音、杂音或喀喇音等特征性听诊表现。这些声音在收缩期的发生时间会因不同的生理或药理操作而有所变化。脱垂开始时间的变化与左心室舒张末期内径的改变有关。