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Effects of glutamate on calcium influx and sequestration/extrusion mechanisms in hippocampal neurons.

作者信息

DeLorenzo R J, Limbrick D D

机构信息

Department of Neurology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298-0599, USA.

出版信息

Adv Neurol. 1996;71:37-46.

PMID:8790787
Abstract
摘要

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Prolonged activation of the N-methyl-D-aspartate receptor-Ca2+ transduction pathway causes spontaneous recurrent epileptiform discharges in hippocampal neurons in culture.
N-甲基-D-天冬氨酸受体-Ca2+转导通路的长期激活会导致培养的海马神经元出现自发性反复癫痫样放电。
Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14482-7. doi: 10.1073/pnas.95.24.14482.