Chant J
Department of Molecular and Cellular Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA.
Curr Opin Cell Biol. 1996 Aug;8(4):557-65. doi: 10.1016/s0955-0674(96)80035-4.
Yeast cells constitute an excellent system for studying cell polarity. They polarize by means of internally programmed patterns of cell division; they polarize chemotropically towards a partner during mating; and they utilize polarity to segregate cell-fate determinants during division. In the past year, considerable progress has been made towards increasing our understanding of the molecular mechanisms underlying each of these processes.
酵母细胞是研究细胞极性的理想系统。它们通过内部编程的细胞分裂模式实现极化;在交配过程中向伴侣进行化学趋向性极化;并且在分裂过程中利用极性来分离细胞命运决定因素。在过去的一年里,我们对这些过程背后的分子机制的理解取得了显著进展。