Okech G, Watson E D, Luckins A G, Makawiti D W
Kenya Trypanosomiasis Research Institute, Kikuyu, Kenya.
Br Vet J. 1996 Jul;152(4):441-51. doi: 10.1016/s0007-1935(96)80038-8.
Six susceptible Galana and five trypanotolerant Orma Boran (Bos indicus) cattle were infected experimentally with Trypanosoma vivax KETRI 2501 by cyclical transmission using Glossina morsitans during early and mid-pregnancy. Four pregnant animals, two of each Boran type were used as controls and remained uninfected throughout the study period. Three out of the six infected susceptible Galana Borans aborted, whilst one had a stillborn calf. None of the trypanotolerant Orma Boran cattle aborted and all carried their pregnancies to term. All control animals produced live calves at term. The mechanisms leading to disruption of reproductive function in susceptible Boran cattle were not clear but could involve a number of factors, including anaemia, weight loss and post-infection decline of plasma progesterone levels. It is concluded that infection with T. vivax disrupts maintenance of pregnancy in susceptible Galana Borans but does not affect maintenance of pregnancy in the Orma Boran, demonstrating their tolerance to infection with T. vivax.
在妊娠早期和中期，使用舌蝇对6头易感的加拉纳牛和5头耐锥虫的奥尔马博拉安（瘤牛）进行了周期性传播实验性感染，使其感染了间日锥虫KETRI 2501。4头怀孕动物，每种博拉安类型各2头作为对照，在整个研究期间未感染。6头感染的易感加拉纳博拉安牛中有3头流产，1头产下死胎。耐锥虫的奥尔马博拉安牛没有一头流产，所有牛都足月分娩。对照动物都足月产下活犊。导致易感博拉安牛生殖功能紊乱的机制尚不清楚，但可能涉及多种因素，包括贫血、体重减轻和感染后血浆孕酮水平下降。得出的结论是，感染间日锥虫会破坏易感加拉纳博拉安牛的妊娠维持，但不影响奥尔马博拉安牛的妊娠维持，表明它们对间日锥虫感染具有耐受性。
