Mohan V, Vijayaprabha R, Rema M
M.V. Diabetes Specialities Centre, Madras, India.
Diabetes Res Clin Pract. 1996 Mar;31(1-3):133-40. doi: 10.1016/0168-8227(96)01215-6.
The prevalence of vascular complications was assessed in 726 South Indian non-insulin dependent diabetes mellitus (NIDDM) patients with over 25 years' duration of diabetes. Retinopathy was detected in 52.0% of patients which included 41.7% with non-proliferative and 10.3% with proliferative diabetic retinopathy. Nephropathy was present in 12.7% and neuropathy in 69.8% of patients. While 32.8% of patients had ischaemic heart disease, the prevalence of peripheral vascular disease was only 15.4%. Multivariate logistic regression analyses showed that serum creatinine was associated with retinopathy, creatinine and post-prandial plasma glucose with nephropathy and post-prandial plasma glucose and age with neuropathy. This is one of the first reports on vascular complications in long-term diabetes from the Indian sub-continent.
对726名病程超过25年的南印度非胰岛素依赖型糖尿病（NIDDM）患者的血管并发症患病率进行了评估。52.0%的患者检测出视网膜病变，其中非增殖性糖尿病视网膜病变占41.7%，增殖性糖尿病视网膜病变占10.3%。12.7%的患者存在肾病，69.8%的患者存在神经病变。32.8%的患者患有缺血性心脏病，外周血管疾病的患病率仅为15.4%。多因素逻辑回归分析显示，血清肌酐与视网膜病变相关，肌酐和餐后血糖与肾病相关，餐后血糖和年龄与神经病变相关。这是来自印度次大陆关于长期糖尿病血管并发症的首批报告之一。
