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小儿患者的游离组织移植

Free tissue transfer in pediatric patients.

作者信息

Serletti J M, Schingo V A, Deuber M A, Carras A J, Herrera H R, Reale V F

机构信息

Strong Memorial Hospital, Rochester, NY 14642, USA.

出版信息

Ann Plast Surg. 1996 Jun;36(6):561-8. doi: 10.1097/00000637-199606000-00001.

Abstract

The majority of reports on free tissue transfer involve adults; few have specifically addressed children. During the past 5 years, 20 free tissue transfers were performed in 19 pediatric patients. Patients ranged in age from 3 to 17 years, with a mean age of 10 years. Eight patients were 6 years and younger; 11 patients were 13 to 17 years old. Soft-tissue defects requiring reconstruction resulted from acute trauma in 12 patients, tumor ablation in 5 patients, infection in 1 patient, and hemifacial atrophy in 1 patient. Soft-tissue defects occurred in the lower extremity in 16 patients, the head and neck in 2 patients, and the upper extremity in 1 patient. The donor tissues included the latissimus dorsi muscle in 7 patients, the radial forearm flap in 7 patients, the rectus abdominis muscle in 4 patients, and the scapular fasciocutaneous flap in 2 patients. All patients received aspirin preoperatively. Mean operative time was 6.5 hours, with a range of 4 to 8 hours. Postoperative heparin infusion was used for 5 days in 7 of the 8 patients age 6 years and younger. All free tissue transfers were successful. One flap to a traumatic foot wound (patient age, 4 years) had a venous thrombosis on the second postoperative day, and was successfully treated with urokinase and heparin infusions and repeat venous anastomosis. There were no other significant morbidities and no mortalities. Hospitalization following free tissue transfer averaged 13 days, with a range of 6 to 37 days. Follow-up has averaged 31 months, with a range of 8 to 59 months. Late complications included a progressive equinus deformity 3 years after a heel reconstruction following a lawn mower injury and a contour deformity following a scapula flap to a gunshot wound of the foot. Sixteen of the 17 lower extremity reconstructions have shown normal growth. No growth disturbances or significant functional losses have occurred at the donor sites. Most patients have maintained normal extremity function including participation in athletics. Special considerations in this group of patients have included subtherapeutic heparin infusion during the postoperative period in young children, minimizing the aesthetic defect at the donor site and providing composite reconstructions whenever possible.

摘要

大多数关于游离组织移植的报告涉及成人;专门针对儿童的报告很少。在过去5年中,对19例儿科患者进行了20次游离组织移植。患者年龄在3至17岁之间,平均年龄为10岁。8例患者年龄在6岁及以下;11例患者年龄在13至17岁之间。需要重建的软组织缺损由12例急性创伤、5例肿瘤切除、1例感染和1例半侧颜面萎缩引起。16例患者的软组织缺损发生在下肢,2例在头颈部,1例在上肢。供体组织包括7例背阔肌、7例桡侧前臂皮瓣、4例腹直肌和2例肩胛筋膜皮瓣。所有患者术前均接受阿司匹林治疗。平均手术时间为6.5小时,范围为4至8小时。8例6岁及以下患者中的7例术后使用肝素输注5天。所有游离组织移植均成功。1例4岁患者足部创伤皮瓣术后第二天出现静脉血栓形成,经尿激酶和肝素输注及重复静脉吻合成功治疗。无其他严重并发症,无死亡病例。游离组织移植后平均住院时间为13天,范围为6至37天。平均随访31个月,范围为8至59个月。晚期并发症包括割草机损伤后足跟重建3年后逐渐出现马蹄足畸形,以及肩胛皮瓣修复足部枪伤后出现外形畸形。17例下肢重建中的16例显示生长正常。供区未发生生长障碍或明显功能丧失。大多数患者保持了正常的肢体功能,包括参加体育运动。该组患者的特殊考虑因素包括幼儿术后亚治疗剂量肝素输注、尽量减少供区美学缺陷以及尽可能提供复合重建。

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