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在缺乏TTTAGGG序列的情况下,葱科植物是如何稳定其染色体末端的?

How do Alliaceae stabilize their chromosome ends in the absence of TTTAGGG sequences?

作者信息

Pich U, Fuchs J, Schubert I

机构信息

Institut für Pflanzengenetik und Kulturpflanzenforschung, Gatersleben.

出版信息

Chromosome Res. 1996 Apr;4(3):207-13. doi: 10.1007/BF02254961.

Abstract

The Arabidopsis-type telomeric repeats (5'-TTTAGGG-3) are highly conserved. In most families of different plant phyla they represent the basic sequence of telomeres that stabilize and protect the chromosome termini. The results presented here show that Alliaceae and some related liliaceous species have no tandemly repeated TTTAGGG sequences. Instead, their chromosomes reveal highly repetitive satellite and/or rDNA sequences at the very ends. These apparently substitute the original plant telomeric sequences in Alliaceae. Both sequence types are very active in homologous recombination and may contribute to the stabilization of chromosome termini via compensation of replication-mediated shortening.

摘要

拟南芥型端粒重复序列(5'-TTTAGGG-3)高度保守。在不同植物门的大多数科中,它们代表着稳定和保护染色体末端的端粒基本序列。本文给出的结果表明,葱科植物和一些相关的百合科物种没有串联重复的TTTAGGG序列。相反,它们的染色体在末端显示出高度重复的卫星序列和/或核糖体DNA序列。这些序列显然替代了葱科植物中原有的植物端粒序列。这两种序列类型在同源重组中都非常活跃,并且可能通过补偿复制介导的缩短来促进染色体末端的稳定。

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