Baba H A, Tietze L, Merkelbach S, Füzesi L
Department of Pathology, University of Münster, Germany.
Gen Diagn Pathol. 1996 Jun;142(1):53-7.
Primary non-Hodgkin lymphoma of bone is an unusual extranodal presentation, and considerable difficulty exists in diagnosing some extranodal osseous lymphomas that develop in the head and neck region. Frequently, malignancies of the jawbones appear clinically as inflammatory diseases. Recognition of these cases usually occurs after the inflammatory-like symptoms have failed to respond to conventional therapy. This case report presents an extranodal non-Hodgkin lymphoma of the maxilla, which clinically imposed as odontogenic infection in a 45-year-old woman. The definite diagnosis was made by histologic means and confirmed by polymerase chain reaction (PCR). The latter is a molecular biologic method, which in unclear cases may be helpful in early differentiation of inflammatory from malignant processes.
原发性骨非霍奇金淋巴瘤是一种不常见的结外表现，诊断头颈部发生的一些结外骨淋巴瘤存在相当大的困难。颌骨恶性肿瘤在临床上常表现为炎症性疾病。这些病例通常在炎症样症状对传统治疗无反应后才得以确诊。本病例报告介绍了一名45岁女性上颌骨的结外非霍奇金淋巴瘤，临床上表现为牙源性感染。通过组织学方法做出明确诊断，并经聚合酶链反应（PCR）证实。后者是一种分子生物学方法，在不明病例中可能有助于早期区分炎症过程和恶性过程。
