Development of B-cell memory and effector function.
作者信息
Lane P
机构信息
Basel Institute for Immunology, Switzerland.
出版信息
Curr Opin Immunol. 1996 Jun;8(3):331-5. doi: 10.1016/s0952-7915(96)80121-x.
PMID:8793988
Abstract
The past year has seen significant advances in our understanding of molecules that both positively and negatively regulate B- and T-cell responses. Of particular interest is the lethal phenotype of CTLA-4-deficient mice, which has illuminated the importance of downregulation of T-cell responses and the increasingly complicated role of CD40 and its ligand in directing both T- and B-cell priming.
摘要
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