体内gp39与CD40的相互作用发生在脾脏的非滤泡区室，对于胸腺依赖性抗体反应和生发中心形成至关重要。 - Suppr | 超能文献

In vivo gp39-CD40 interactions occur in the non-follicular compartments of the spleen and are essential for thymus dependent antibody responses and germinal center formation.

作者信息

van den Eertwegh A J, Van Meurs M, Foy T M, Noelle R J, Boersma W J, Claassen E

机构信息

Dept. Immunology and Medical Microbiology, TNO-MBL, Rijswijk, The Netherlands.

出版信息

Adv Exp Med Biol. 1994;355:75-80. doi: 10.1007/978-1-4615-2492-2_13.

DOI:10.1007/978-1-4615-2492-2_13

Abstract

摘要

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In vivo gp39-CD40 interactions occur in the non-follicular compartments of the spleen and are essential for thymus dependent antibody responses and germinal center formation.体内gp39与CD40的相互作用发生在脾脏的非滤泡区室，对于胸腺依赖性抗体反应和生发中心形成至关重要。

Adv Exp Med Biol. 1994;355:75-80. doi: 10.1007/978-1-4615-2492-2_13.

2

In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions.体内CD40与gp39的相互作用对于胸腺依赖性体液免疫至关重要。I. CD40配体的体内表达、细胞因子及抗体产生描绘了同源T细胞与B细胞相互作用的位点。

J Exp Med. 1993 Nov 1;178(5):1555-65. doi: 10.1084/jem.178.5.1555.

3

gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory.gp39与CD40的相互作用对于生发中心的形成和B细胞记忆的发展至关重要。

J Exp Med. 1994 Jul 1;180(1):157-63. doi: 10.1084/jem.180.1.157.

4

CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation.CD40及其配体，是胸腺依赖性B细胞活化所必需的配体-受体对。

Immunol Today. 1992 Nov;13(11):431-3. doi: 10.1016/0167-5699(92)90068-I.

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In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39.体内CD40与gp39的相互作用对于胸腺依赖性体液免疫至关重要。II. 抗CD40配体gp39抗体对体液免疫反应的长期抑制作用。

J Exp Med. 1993 Nov 1;178(5):1567-75. doi: 10.1084/jem.178.5.1567.

6

Non-antigen signals for B-cell growth and differentiation to antibody secretion.B细胞生长及分化为抗体分泌细胞的非抗原信号。

Curr Opin Immunol. 1993 Jun;5(3):439-44. doi: 10.1016/0952-7915(93)90066-2.

7

Memory B cell development but not germinal center formation is impaired by in vivo blockade of CD40-CD40 ligand interaction.体内阻断CD40-CD40配体相互作用会损害记忆B细胞的发育，但不会影响生发中心的形成。

J Exp Med. 1994 Jul 1;180(1):141-55. doi: 10.1084/jem.180.1.141.

8

Signaling via major histocompatibility complex class II molecules and antigen receptors enhances the B cell response to gp39/CD40 ligand.通过主要组织相容性复合体II类分子和抗原受体发出的信号增强了B细胞对gp39/CD40配体的反应。

Eur J Immunol. 1995 May;25(5):1230-8. doi: 10.1002/eji.1830250515.

9

The molecular basis for T cell help in humoral immunity: CD40 and its ligand, gp39.体液免疫中T细胞辅助的分子基础：CD40及其配体gp39。

J Clin Immunol. 1993 May;13(3):165-74. doi: 10.1007/BF00919969.

10

Activation of B cells by 1 microm particulate lysozyme or peptides: a Th-dependent pathway requiring CD40-CD40 ligand interaction.1微米大小的颗粒状溶菌酶或肽对B细胞的激活：一条依赖Th细胞的途径，需要CD40-CD40配体相互作用。

Int Immunol. 1998 Aug;10(8):1111-9. doi: 10.1093/intimm/10.8.1111.

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