Roeper J, Pongs O
Zentrum für Molekulare Neurobiologie, Institut für neurale Signalverarbeitung, Martinistrasse 52, Haus 42, D-20246 Hamburg, Germany.
Curr Opin Neurobiol. 1996 Jun;6(3):338-41. doi: 10.1016/s0959-4388(96)80117-6.
The past year has witnessed some significant improvements in our understanding of the molecular diversity, subunit composition, and functional properties of K+ channels in heterologous expression systems. Immunocytochemical studies have yielded important information on the localization of K+ channel proteins to synaptic terminals in mammalian brain. Although a coherent picture of native presynaptic K+ channels' function in the mammalian central nervous system is not yet available, it may emerge from improvements in patch-clamp techniques and new applications of targeted knock-out technologies.
