通过内分泌细胞电容测量研究胞吐作用和胞吞作用中的快速步骤。
Fast steps in exocytosis and endocytosis studied by capacitance measurements in endocrine cells.
作者信息
Henkel A W, Almers W
机构信息
Max-Planck-Institut für Medizinische Forschung, Jahnstrasse 29, 69120 Heidelberg, Germany.
出版信息
Curr Opin Neurobiol. 1996 Jun;6(3):350-7. doi: 10.1016/s0959-4388(96)80119-x.
PMID:8794084
Abstract
The past year has witnessed progress in identifying late steps in exocytosis that are so short-lived as to be difficult to study biochemically. Recent studies have also revealed a novel and surprisingly fast mechanism of endocytosis that may be triggered by a rise in the intracellular concentration of Ca2+ and that retrieves exocytosed membrane in seconds.
摘要
过去一年里，在确定胞吐作用后期步骤方面取得了进展，这些步骤持续时间极短，难以用生物化学方法进行研究。最近的研究还揭示了一种新的、惊人的快速内吞作用机制，该机制可能由细胞内Ca2+浓度升高触发，并能在数秒内回收胞吐的膜。
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