转运蛋白中的通道。

Channels in transporters.

作者信息

Sonders M S, Amara S G

机构信息

Howard Hughes Medical Institute and Vollum Institute, Oregon Health Sciences University, Portland, Oregon 97201, USA.

出版信息

Curr Opin Neurobiol. 1996 Jun;6(3):294-302. doi: 10.1016/s0959-4388(96)80111-5.

DOI:10.1016/s0959-4388(96)80111-5

PMID:8794089

Abstract

Recent electrophysiological investigations of plasma membrane neurotransmitter transporters have shown that carriers can function in ways similar to ion channels. The results of these studies reveal underlying mechanisms not encompassed by classic carrier models and support an emerging view that transporter-mediated ionic currents may contribute to signaling in the nervous system.

摘要

近期对质膜神经递质转运体的电生理研究表明，载体的功能方式可能与离子通道类似。这些研究结果揭示了经典载体模型未涵盖的潜在机制，并支持了一种新出现的观点，即转运体介导的离子电流可能在神经系统信号传导中发挥作用。