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尼扎替丁、克拉霉素和枸橼酸铋钾三联疗法根除十二指肠溃疡患者幽门螺杆菌的疗效——初步报告

Efficacy of nizatidine, clarithromycin and bismuth subcitrate therapy for Helicobacter pylori eradication in duodenal ulcer patients--a preliminary report.

作者信息

Papp J, Juhasz L, Lakatos L, Lonovits J, Szekely I, Tarnok F, Tulassay Z, Varkonyi T

机构信息

1st Department of Medicine, Semmelweis University Medical School, Budapest, Hungary.

出版信息

Br J Clin Pract. 1996 Jul-Aug;50(5):249-53.

PMID:8794601
Abstract

The triple combination of nizatidine, clarithromycin, and bismuth subcitrate resulted in an ulcer healing rate of 98% and an H. pylori eradication rate of 90%. Corresponding 'intention-to-treat' figures were 92% and 84%, respectively. These results suggest that further studies, shorter in duration, using lower dosages, and possibly testing other combinations with a double-blind methodology, are required.

摘要

尼扎替丁、克拉霉素和枸橼酸铋钾三联疗法的溃疡愈合率为98%,幽门螺杆菌根除率为90%。相应的“意向性治疗”数据分别为92%和84%。这些结果表明,需要进行进一步的研究,研究持续时间更短、使用更低剂量,并可能采用双盲方法测试其他组合。

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