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深度低温后的氧摄取

Oxygen uptake following deep hypothermia.

作者信息

Abbott T R

出版信息

Anaesthesia. 1977 Jun;32(6):524-32. doi: 10.1111/j.1365-2044.1977.tb09999.x.

DOI:10.1111/j.1365-2044.1977.tb09999.x
PMID:879464
Abstract

Oxygen uptake of the body (Vo2) was measured in 9 children undergoing surgical correction of congenital heart lesions using cardiopulmonary bypass and deep hypothermia at 20 degrees tc with circulatory arrest. Initial levels of Vo2 following circulatory arrest were found to be four times greater than would have been expected from the normal relationship between Vo2 and body temperature, but within 8-10 minutes had fallen to normal levels. The quantity of oxygen taken up by the body during this time is similar to theoretical values for the quantity of oxygen inphysical solution, at 20 degrees C, in the tissues. It is postulated that during deep hypothermia the increased amount of oxygen in physical solution in the body plays an important part in preventing tissue damage during circulatory arrest.

摘要

对9名接受先天性心脏病手术矫正的儿童进行了身体摄氧量(Vo2)测量,这些手术采用体外循环和20摄氏度深低温并伴有循环停止。发现循环停止后Vo2的初始水平比根据Vo2与体温的正常关系所预期的要大四倍,但在8 - 10分钟内已降至正常水平。在此期间身体摄取的氧气量与20摄氏度时组织中物理溶解的氧气量的理论值相似。据推测,在深低温期间,身体中物理溶解的氧气量增加在防止循环停止期间的组织损伤中起重要作用。

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引用本文的文献

1
Decreased critical mixed venous oxygen tension and critical oxygen transport during induced hypothermia in pigs.
J Clin Monit. 1986 Jul;2(3):155-68. doi: 10.1007/BF01620548.
2
Theoretical analysis of oxygen transport during hypothermia.低温期间氧输送的理论分析
J Clin Monit. 1986 Jan;2(1):30-43. doi: 10.1007/BF01619175.