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通过胃管依次给马施用噻苯达唑和敌百虫后,对其抗寄生虫活性进行的关键试验。

Critical tests of the antiparasitic activity of thiabendazole and trichlorfon sequentially administered to horses via stomach tube.

作者信息

Lyons E T, Drudge J H, Tolliver S C

出版信息

Am J Vet Res. 1977 Jun;38(6):721-3.

PMID:879569
Abstract

Thirteen critical tests were conducted in horses naturally infected with helminths and bots. Single doses of thiabendazole (44 mg/kg of body weight) and trichlorfon (40 mg/kg of body weight) powder formulations were administered as suspensions sequentially given via stomach tube to evaluate the efficacy of the combination against the large parasites of horses. Parasite removal efficacies were 100% against 2nd instar Gasterophilus intestinalis and 2nd and 3rd instar Gasterophilus nasalis and 82 to 100% against 3rd instar G intestinals. There were complete removals of mature and immature Parascaris equorum and mature Oxyuris equi. Removal efficacies against Strongylus vulgaris were 89 to 100% and against Strongylus edentatus, 82 to 100%. Of 2 horses infected with Strongylus equinus, removals were 72 and 100%. Seven of the 13 horses treated had transient, semi-liquid feces during the posttreatment hours 1 through 24.

摘要

对自然感染蠕虫和胃蝇蛆的马匹进行了13项关键试验。将单剂量的噻苯达唑(44毫克/千克体重)和敌百虫(40毫克/千克体重)粉剂配制成悬浮液,通过胃管依次给药,以评估该组合对马体内大型寄生虫的疗效。对二龄期马胃蝇、二龄和三龄期鼻胃蝇的驱虫效果为100%,对三龄期肠胃蝇的驱虫效果为82%至100%。马副蛔虫的成熟和未成熟个体以及马尖尾线虫的成熟个体被完全清除。对普通圆线虫的清除率为89%至100%,对无齿圆线虫的清除率为82%至100%。在感染马圆线虫的2匹马中,清除率分别为72%和100%。13匹接受治疗的马中有7匹在治疗后的1至24小时内出现短暂的半流质粪便。

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Am J Vet Res. 1977 Jun;38(6):721-3.
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