阿托品对犬足三里穴针刺及电针刺激的心血管效应
Cardiovascular effects of atropine on acupuncture, needling with electrostimulation, at Tsu San Li (St-36) in dogs.
作者信息
Clifford D H, Lee M O, Lee D C
出版信息
Am J Vet Res. 1977 Jun;38(6):845-9.
Acupuncture, needling with electrostimulation, at Tsu San Li (St-36) produced (1) significant decrease in cardiac output, (2) decrease in stroke volume, (3) increase in total peripheral resistance, and (4) minimal changes in heart rate, mean arterial pressure, pulse pressure, and central venous pressure in dogs under halothane anesthesia. Atropine given alone and given before acupuncture at Tsu San Li (St-36) produced (1) early significant increase in cardiac output, (2) early significant increase in heart rate, (3) increase in mean arterial pressure, (4) decrease in total peripheral resistance, and (5) minimal changes in stroke volume, pulse pressure, and central venous pressure in anesthetized dogs. It was concluded that the effects of acupuncture at Tsu San Li (St-36) were parasympathomimetic-like and that these effects could be blocked by atropine, a parasympatholytic drug.
在氟烷麻醉的犬中，针刺足三里穴（St-36）并施以电刺激，可导致：（1）心输出量显著降低；（2）每搏输出量降低；（3）总外周阻力增加；（4）心率、平均动脉压、脉压和中心静脉压仅有微小变化。单独给予阿托品以及在针刺足三里穴（St-36）之前给予阿托品，可使麻醉犬出现：（1）早期心输出量显著增加；（2）早期心率显著增加；（3）平均动脉压升高；（4）总外周阻力降低；（5）每搏输出量、脉压和中心静脉压仅有微小变化。得出的结论是，针刺足三里穴（St-36）的效应类似拟副交感神经作用，且这些效应可被副交感神经阻滞剂阿托品阻断。
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