Párraga Quiles M J, Sánchez Pedraza R, Barreiro Lucas J C, Cañete Estrada R, Fernández Gutiérrez F, Zapatero Martínez M, Gallardo Galera J M
Dpto. de Pediatría, Hospital Universitario Reina Sofía, Córdoba.
An Esp Pediatr. 1996 May;44(5):482-4.
To analyze prospectively the incidence and outcome of retinopathy of prematurity (ROP) in preterm infants admitted to a neonatal intensive care unit.
A high risk group of infants with birth weights less than 1,500 g, and/or a gestational age less than 30 weeks, was studied. Ophthalmoscopic examination was performed at six weeks of age. Frequent ophthalmoscopic examinations were then performed depending on the gravity of the ROP.
ROP was found in 14 of the 20 preterm infants (70%). Two developed stage 3 and none of them stage 4 or 5. Cryotherapy for ROP was not used. None of the infants progressed to advanced stages of ROP and complete resolution was the rule.
Despite the low incidence of advanced stages of ROP in our study, we suggest that all preterm infants less than 1,500 g and/or 30 weeks of gestational age, should be screened for ROP and repeated ophthalmoscopic examination performed in order to evaluate the progression and treatment of ROP.
前瞻性分析入住新生儿重症监护病房的早产儿视网膜病变(ROP)的发病率及转归。
研究对象为出生体重小于1500克和/或胎龄小于30周的高危组婴儿。在婴儿6周龄时进行眼底检查。然后根据ROP的严重程度进行频繁的眼底检查。
20例早产儿中有14例(70%)发生ROP。2例发展为3期,无1例发展为4期或5期。未使用ROP冷冻疗法。所有婴儿均未进展至ROP晚期,通常完全消退。
尽管本研究中ROP晚期发病率较低,但我们建议,所有出生体重小于1500克和/或胎龄小于30周的早产儿均应接受ROP筛查,并进行重复眼底检查,以评估ROP的进展及治疗情况。