Aso Y, Sato A, Tayama K, Takanashi K, Satoh H, Takemura Y
Department of Medicine, Dokkyo Koshigaya Hospital, Dokkyo University School of Medicine.
Intern Med. 1996 May;35(5):392-5. doi: 10.2169/internalmedicine.35.392.
We describe herein a case of parathyroid carcinoma accompanied with metastatic calcification identified by technetium-99m methylene diphosphonate (Tc-99m MDP) scintigraphy in the lungs, kidneys and stomach. Parathyroid carcinoma remains a rare disorder despite the increased prevalence of primary hyperparathyroidism. Metastatic calcification is noted infrequently even in primary hyperparathyroidism and it may cause respiratory failure. Tc-99m MDP scintigraphy three months after surgery showed a complete disappearance of Tc-99m uptake in the stomach and an obvious reduction in the kidneys but no significant change in the lungs, indicating metastatic calcification can be reversibly reabsorbed. This case indicates that the adequate excision of parathyroid carcinoma as well as the early detection of metastatic calcification by Tc-99m MDP are obligatory.
我们在此描述一例甲状旁腺癌伴发肺、肾及胃转移性钙化的病例，该病例通过锝-99m亚甲基二膦酸盐（Tc-99m MDP）肺闪烁显像得以确诊。尽管原发性甲状旁腺功能亢进症的患病率有所上升，但甲状旁腺癌仍然是一种罕见的疾病。即使在原发性甲状旁腺功能亢进症中，转移性钙化也不常见，且可能导致呼吸衰竭。术后三个月的Tc-99m MDP闪烁显像显示胃内Tc-99m摄取完全消失，肾脏摄取明显减少，但肺部无明显变化，表明转移性钙化可被可逆性重吸收。该病例表明，充分切除甲状旁腺癌以及通过Tc-99m MDP早期发现转移性钙化是必要的。
