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急性上颌窦炎早期所获积液中免疫球蛋白和补体包被的细菌。

Immunoglobulin- and complement-coated bacteria in effusions obtained during the early course of acute maxillary sinusitis.

作者信息

Rantala H, Stenfors L E, Räisänen S

机构信息

Department of Otolaryngology, Tampere University, Finland.

出版信息

ORL J Otorhinolaryngol Relat Spec. 1996 May-Jun;58(3):151-6. doi: 10.1159/000276816.

DOI:10.1159/000276816
PMID:8797219
Abstract

Fifty samples of maxillary sinus effusion from 40 patients (median age 29 years; 26 females and 14 males) with acute maxillary sinusitis (AMS) were subjected to quantitative and qualitative bacteriological analysis. Furthermore, bacteria coated with immunoglobulin (IgG, secretory IgA, IgM) or complement (C3b) were evaluated using an immunofluorescence assay. 72% of the samples harboured detectable bacteria, the most common pathogens being Streptococcus pneumoniae and non-typable Haemophilus influenzae. Of the bacteria-positive samples, 28% harboured immunoglobulin-coated bacteria. During the first weeks of an AMS infection, the present immunoglobulins are insufficient to protect the maxillary sinuses.

摘要

对40例急性上颌窦炎(AMS)患者(中位年龄29岁;26名女性和14名男性)的50份上颌窦积液样本进行了定量和定性细菌学分析。此外,使用免疫荧光测定法评估了包被有免疫球蛋白(IgG、分泌型IgA、IgM)或补体(C3b)的细菌。72%的样本中含有可检测到的细菌,最常见的病原体是肺炎链球菌和不可分型的流感嗜血杆菌。在细菌阳性样本中,28%含有包被有免疫球蛋白的细菌。在AMS感染的最初几周内,现有的免疫球蛋白不足以保护上颌窦。

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