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老年患者的电视辅助胸腔手术。307例病例回顾。

Video-assisted thoracic surgery in the elderly. A review of 307 cases.

作者信息

Jaklitsch M T, DeCamp M M, Liptay M J, Harpole D H, Swanson S J, Mentzer S J, Sugarbaker D J

机构信息

Division of Thoracic Surgery, Brigham and Women's Hospital, Boston, MA

出版信息

Chest. 1996 Sep;110(3):751-8. doi: 10.1378/chest.110.3.751.

Abstract

STUDY OBJECTIVE

The objective of the study was to investigate the impact of video-assisted thoracic surgery (VATS) on age-related morbidity and mortality for thoracic surgical procedures.

DESIGN

Prospective data were collected on 896 consecutive VATS procedures from July 1991 to June 1994. Daily in-hospital, postoperative data collection by a full-time thoracic surgical nurse and postdischarge follow-up in a thoracic surgery clinic at 1 and 6 weeks were done.

PATIENTS

On 296 patients aged 65 or older, 307 procedures were performed. One hundred nine procedures were performed on patients between 65 and 69 years, 110 on patients between 70 and 74 years, 55 on patients between 75 and 79 years, and 33 on those between 80 and 90 years.

MEASUREMENTS AND RESULTS

The population was divided into four cohorts of 5-year age spans for analysis. Comparison was made with Fisher's Exact Test. Overall, 61% of the 307 procedures were for pulmonary disease. There were 32 anatomic lung resections (VATS lobectomies or segmentectomies), 156 extra-anatomic lung resections (thoracoscopic wedge or bullectomy), 78 procedures for pleural disease (25%), 27 mediastinal dissections (9%), and 14 pericardial windows (5%). There was a trend toward a lower mean FEV1 with increasing age. There were 3 deaths; overall mortality was less than 1%. There were 4 conversions to open thoracotomy (1%). Complications occurred with 45 procedures (15% morbidity). Twenty-two operations (7%) were associated with major complications adding to the length of stay and 27 procedures (9%) had minor complications. Median length of stay after VATS was 4 days for patients aged 65 to 79 years and 5 days for those aged 80 to 90 years. Morbidity and mortality were unrelated to age.

CONCLUSIONS

The 30-day operative mortality is superior to previous reports of standard thoracotomy. Morbidity is low and length of hospital stay appears improved. VATS techniques may be safer than open thoracotomy in the aged. Age alone should not be a contraindication to operative intervention.

摘要

研究目的

本研究的目的是调查电视辅助胸腔镜手术(VATS)对胸外科手术中与年龄相关的发病率和死亡率的影响。

设计

收集了1991年7月至1994年6月连续896例VATS手术的前瞻性数据。由一名专职胸外科护士进行每日住院期间及术后数据收集,并在胸外科门诊于术后1周和6周进行出院后随访。

患者

对296例65岁及以上患者进行了307例手术。其中,65至69岁患者进行了109例手术,70至74岁患者进行了110例手术,75至79岁患者进行了55例手术,80至90岁患者进行了33例手术。

测量与结果

将研究人群按5岁年龄跨度分为四个队列进行分析。采用Fisher精确检验进行比较。总体而言,307例手术中有61%是针对肺部疾病。其中有32例解剖性肺切除术(VATS肺叶切除术或肺段切除术),156例非解剖性肺切除术(胸腔镜楔形切除术或肺大疱切除术),78例胸膜疾病手术(25%),27例纵隔清扫术(9%),以及14例心包开窗术(5%)。随着年龄增长,平均第一秒用力呼气容积(FEV1)有降低趋势。有3例死亡;总体死亡率低于1%。有4例转为开胸手术(1%)。45例手术出现并发症(发病率为15%)。22例手术(7%)伴有严重并发症,延长了住院时间,27例手术(9%)有轻微并发症。65至79岁患者VATS术后中位住院时间为4天,80至90岁患者为5天。发病率和死亡率与年龄无关。

结论

30天手术死亡率优于以往标准开胸手术的报道。发病率低,住院时间似乎有所缩短。VATS技术在老年患者中可能比开胸手术更安全。年龄本身不应成为手术干预的禁忌证。

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