DeCamp M M, Jaklitsch M T, Mentzer S J, Harpole D H, Sugarbaker D J
Division of Thoracic Surgery, Brigham and Women's Hospital, Boston, MA 02115, USA.
J Am Coll Surg. 1995 Aug;181(2):113-20.
The application of video-endoscopy to general thoracic surgery is radically changing the approach to many benign and malignant diseases of the chest. Since July 1991, we have performed 794 purely thoracoscopic and 101 video-assisted thoracic surgical (VATS) procedures on 860 patients.
Comprehensive, prospectively acquired data examining the specific indications for and outcomes of this new technique were prospectively entered into a thoracic surgical database. Preoperative, intraoperative, postoperative, and outcome variables were studied for the entire group as well as three high-risk cohorts: age over 70 years (n = 198), forced expiratory volume in one second (FEV1) of less than 1 L (n = 46), and Karnofsky performance index of less than 8 (n = 61).
The 895 cases involved 449 men and 446 women of ages 15 to 89 years (mean 56 +/- 16 years standard deviation). The indications for surgery were diagnostic in 501 cases (56 percent), therapeutic in 244 cases (27 percent), and both diagnostic and therapeutic in an additional 150 cases (17 percent). The specific procedures performed were operations on the lung (569 cases), pleura (196 cases), esophagus (42 cases), mediastinum (51 cases), and pericardium (37 cases). Fifty-seven percent of the procedures were for a malignant process and 43 percent were for benign or infectious pathology. There were nine deaths for a series operative mortality rate of 1.0 percent. Thirteen patients (1.4 percent) required conversion to a limited thoracotomy for technical reasons. There were 127 complications in 121 patients yielding a morbidity rate in all patients of 14 percent. Mortality rates in the elderly, poor lung function, and depressed performance index cohorts were 1.5, 2.1, and 9.8 percent, respectively. Morbidity rates in these high-risk populations were 19, 30, and 18 percent, respectively. The median postoperative length of stay was three days after closed thoracoscopy and five days after VATS resection.
These data underscore the flexibility, safety, efficacy, and potential for cost savings of videoscopic surgery in patients with thoracic diseases. The ability to perform excisional biopsy improves diagnostic specificity and sensitivity to nearly 100 percent. Video-assisted thoracic surgical techniques also offer a minimally invasive procedure with acceptable risk to patients heretofore inoperable by standard thoracotomy.
电视胸腔镜在普通胸外科的应用正在从根本上改变许多胸部良恶性疾病的治疗方法。自1991年7月以来,我们已对860例患者实施了794例单纯胸腔镜手术和101例电视辅助胸腔手术(VATS)。
前瞻性收集的关于这项新技术的具体适应证和结果的综合数据被前瞻性地录入胸外科数据库。对整个组以及三个高危队列研究术前、术中、术后和结果变量:年龄超过70岁(n = 198)、一秒用力呼气量(FEV1)小于1L(n = 46)和卡氏功能状态评分小于8(n = 61)。
895例患者中,男性449例,女性446例,年龄15至89岁(平均56±16岁标准差)。手术适应证中,诊断性的有501例(56%),治疗性的有244例(27%),诊断兼治疗性的有150例(17%)。具体实施的手术包括肺部手术(569例)、胸膜手术(196例)、食管手术(42例)、纵隔手术(51例)和心包手术(37例)。57%的手术针对恶性病变,43%针对良性或感染性病变。共有9例死亡,系列手术死亡率为1.0%。13例患者(1.4%)因技术原因转为有限开胸手术。121例患者出现127例并发症,所有患者的发病率为14%。老年、肺功能差和功能状态评分低的队列中的死亡率分别为1.5%、2.1%和9.8%。这些高危人群的发病率分别为19%、30%和18%。胸腔镜手术后中位住院时间为3天,VATS切除术后为5天。
这些数据强调了电视胸腔镜手术在胸部疾病患者中的灵活性、安全性、有效性以及潜在的成本节约。进行切除活检的能力将诊断特异性和敏感性提高到近100%。电视辅助胸腔手术技术还提供了一种微创手术,对以往无法通过标准开胸手术治疗的患者具有可接受的风险。