Goubau P, Vandamme A M, Desmyter J
Department of Microbiology, University Hospitals, Leuven, Belgium.
J Acquir Immune Defic Syndr Hum Retrovirol. 1996;13 Suppl 1:S242-7. doi: 10.1097/00042560-199600001-00036.
In human and simian T-lymphotropic viruses (HTLV and STLV), collectively referred to as primate T-lymphotropic viruses (PTLV), four distinct clades can be distinguished: PTLV-I, PTLV-II, and the newly discovered divergent STLVs isolated from hamadryas baboons and from bonobos (pygmy chimpanzees). The hamadryas STLV is clearly distinct from types I and II, in terms both of sequence divergence and of genomic structure, and would qualify as a separate type, provisionally called PTLV-L. The bonobo STLV is closer to, although clearly distinct from, PTLV-II, at present known only in humans. While PTLV-II, PTLV-L, and the bonobo STLV appear presently to be species specific, PTLV-I has spread during its evolution through repeated interspecies transmissions between primates and is now present in many species of Old World monkeys and apes and in humans. The human subtypes of PTLV-I arose from at least three acquisitions from separate simian reservoirs.
在人类嗜T淋巴细胞病毒（HTLV）和猿猴嗜T淋巴细胞病毒（STLV）中，统称为灵长类嗜T淋巴细胞病毒（PTLV），可区分出四个不同的进化枝：PTLV-I、PTLV-II，以及新发现的从阿拉伯狒狒和倭黑猩猩（侏儒黑猩猩）中分离出的不同的STLV。阿拉伯狒狒STLV在序列差异和基因组结构方面都明显不同于I型和II型，有资格作为一个单独的类型，暂称为PTLV-L。倭黑猩猩STLV与PTLV-II更接近，尽管明显不同，目前仅在人类中已知。虽然PTLV-II、PTLV-L和倭黑猩猩STLV目前似乎具有物种特异性，但PTLV-I在其进化过程中通过灵长类动物之间反复的种间传播而扩散，现在存在于许多旧世界猴和猿以及人类物种中。PTLV-I的人类亚型至少源自从不同猿类宿主的三次获得。
