Förström L, Winkelmann R K
Arch Dermatol. 1977 Jul;113(7):909-17.
Thirty-four patients had histopathologic findings of acute panniculitis. 15 had clinical findings of erythema nodosum; 6 had infectious lesions; and 5 had Weber-Christian-like conditions with recurrent febrile suppurative or nonsuppurative nodular eruptions; 3 of the 5 had amylase and lipase enzyme abnormalities with or without pancreatic disease. Five additional patients had acute panniculitis that would be termed "deythema induratum" or "nodular vasculitis" by most clinicians, and the subsequent pathologic findings and courses were consistent with this view. Two patients had limited, traumatic panniculitis, forming a distinctive group, but trauma was a factor in lesion formation in all groups, and one patient had vasculitis. Whereas acute panniculitis, with or without fat necrosis, may be associated with many inflammatory syndromes of the skin and subcutaneous tissue and may rarely occur in all, the most common relationship is with erythema nodosum in its most acute forms.
34例患者有急性脂膜炎的组织病理学表现。15例有结节性红斑的临床表现；6例有感染性病变；5例有类似Weber-Christian病的情况，表现为反复发热性化脓性或非化脓性结节性皮疹；这5例中的3例有淀粉酶和脂肪酶异常，伴或不伴有胰腺疾病。另外5例患者有急性脂膜炎，大多数临床医生会将其称为“硬结性红斑”或“结节性血管炎”，随后的病理表现和病程与这一观点相符。2例患者有局限性创伤性脂膜炎，形成一个独特的组，但创伤是所有组病变形成的一个因素，还有1例患者有血管炎。急性脂膜炎，无论有无脂肪坏死，可能与皮肤和皮下组织的许多炎症综合征相关，且在所有情况中可能很少发生，最常见的关系是与最急性形式的结节性红斑相关。
