Healey M, Warton B, Taylor N
Monash Medical Centre, Clayton, Victoria.
Aust N Z J Obstet Gynaecol. 1996 May;36(2):179-81. doi: 10.1111/j.1479-828x.1996.tb03281.x.
Fifty-five patients were randomized in a double-blinded manner to large loop excision of the transformation zone (LLETZ) (29 patients) or radical cervical diathermy with fulgaration (RCDF) (26 patients) for treatment of cervical intraepithelial neoplasia (CIN). Patients completed a 2-month diary of symptoms and completed a 10-week postoperative questionnaire. White vaginal discharge lasted 7.3 (4.6) days (SD) for RCDF compared to 3.4 (1.6) days (SD) for LLETZ. There was no significant difference in any other symptoms on analysis This appears to be the first report clearly assessing the length and severity of postoperative symptoms following LLETZ or RCDF. There is no reason on length and severity of postoperative symptoms to choose 1 of these 2 treatment methods over the other.
55例患者被随机双盲分为两组，分别接受转化区大环形切除术（LLETZ）（29例）或宫颈根治性电凝电灼术（RCDF）（26例），以治疗宫颈上皮内瘤变（CIN）。患者完成了一份为期2个月的症状日记，并填写了一份术后10周的问卷。RCDF组白色阴道分泌物持续时间为7.3（4.6）天（标准差），而LLETZ组为3.4（1.6）天（标准差）。分析显示，其他任何症状均无显著差异。这似乎是第一份明确评估LLETZ或RCDF术后症状持续时间和严重程度的报告。就术后症状的持续时间和严重程度而言，没有理由选择这两种治疗方法中的一种而不选另一种。
