Bujdák J, Rode B M
Institute of Inorganic Chemistry, Slovak Academy of Sciences, 842 36 Bratislava, Slovakia.
J Mol Evol. 1996 Oct;43(4):326-33. doi: 10.1007/BF02339007.
Clay-catalyzed glycine and diglycine oligomerizations were performed as drying/wetting cycles at 80 degrees C. Two trioctahedral smectites (hectorite and saponite), three pure montmorillonites, a ferruginous smectite, an Fe(II)-rich smectite, and three smectites containing goethite admixture were used as catalysts. Highest peptide bond formation was found with trioctahedral smectites. About 7% of glycine was converted to diglycine and diketopiperazine on hectorite after 7 days. In the case of dioctahedral smectites, highest yields were achieved using clays with a negative-layer charge localized in the octahedral sheets (up to 2% of converted glycine after 7 days). The presence of Fe(II) in clay is reflected in a higher efficiency in catalyzing amino acid dimerization (about 3.5% of converted glycine after 7 days). The possible significance of the results for prebiotic chemistry is discussed.
在80摄氏度下，以干燥/湿润循环的方式进行了粘土催化的甘氨酸和二甘氨酸寡聚反应。使用了两种三八面体蒙脱石（锂蒙脱石和皂石）、三种纯蒙脱石、一种铁质蒙脱石、一种富含Fe(II)的蒙脱石以及三种含有针铁矿混合物的蒙脱石作为催化剂。发现三八面体蒙脱石的肽键形成量最高。7天后，锂蒙脱石上约7%的甘氨酸转化为二甘氨酸和二酮哌嗪。对于二八面体蒙脱石，使用八面体片中存在负层电荷的粘土可实现最高产率（7天后转化的甘氨酸高达2%）。粘土中Fe(II)的存在反映在催化氨基酸二聚化的效率更高（7天后约3.5%的甘氨酸转化）。讨论了这些结果对益生元化学的可能意义。
