Böhrer H, Schmidt H, Bach A, Böttiger B W, Motsch J
Department of Anesthesia, University of Heidelberg, Germany.
Hepatogastroenterology. 1996 May-Jun;43(9):515-8.
Sepsis is usually treated with surgical drainage, antibiotics, oxygenation optimization and volume resuscitation. Recent monoclonal and polyclonal anti-bodies have been used to treat sepsis by neutralizing the endotoxins and cytokines found in septic patients. This method does not significantly reduce mortality except in certain sub-populations of the treatment groups. We introduced a combination approach for sepsis treatment. This adjuvant therapy consists of polyclonal human immunoglobins together with infusion of low-dose hydrocortisone. This paper reports the results of this treatment in two different cases.
