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多环芳烃的致癌活性与其在DNA最低三重态范围内的过渡态的某些性质之间存在非常显著的相关性。

A very significant correlation between carcinogenic activity of polycyclic hydrocarbons and certain properties of their transition states in the range of the lowest triplet states of the DNA.

作者信息

Popp F A

出版信息

Arch Geschwulstforsch. 1977;47(2):97-105.

PMID:879983
Abstract

A very significant correlation between carcinogenic power of polycyclic aromatic hydrocarbons and their probability of photoinduced double resonance transitions in the UV-range of about 3 to 3.5 eV is shown. The resonance can be interpreted in terms of the lowest triplet state energy of thymine at 3.25 eV and the energy difference between the triplet states of A--T and G--C base pairs. The correlation has been predicted from a hypothesis which describes cell communication by photon interaction within a cell population.

摘要

结果表明,多环芳烃的致癌能力与其在约3至3.5电子伏特紫外线范围内光致双共振跃迁的概率之间存在非常显著的相关性。这种共振可以用胸腺嘧啶在3.25电子伏特的最低三重态能量以及A-T和G-C碱基对三重态之间的能量差来解释。这种相关性是根据一个假设预测出来的,该假设描述了细胞群体内通过光子相互作用进行的细胞通讯。

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