Kurata A, Miyasaka Y, Tanaka C, Ohmomo T, Yada K, Kan S
Department of Neurosurgery, Kitasato University School of Medicine, Kanagawa, Japan.
Acta Neurochir (Wien). 1996;138(5):549-54. doi: 10.1007/BF01411175.
Does the absolute value of the stump pressure (post-occlusion back pressure) become a useful index of a good collateral circulation? The authors continuously monitored the mean arterial pressure before, during and after 20-minute balloon test occlusion in 24 patients. The stump pressure was then compared with the results of 99mTc-hexa-methyl propyleneamine (99mTc-HMPAO) single photon emission computed tomography (SPECT) performed after 20 minutes of test occlusion. Patients who failed to tolerate even brief periods of carotid occlusion and showed asymmetric decreases in cerebral blood flow (CBF) on SPECT were divided into high and moderate risk groups. Those with no significant change in CBF on the occluded side formed the minimum risk group. Mean stump pressure was over 50 mmHg in three of a total of 13 patients in the high and moderate risk groups, and below 50 mmHg in two of the 11 patients in the minimum risk group. The ratios of the initial mean stump pressure to the pre-occlusion mean arterial pressure (%) and of the final mean stump pressure at the end of occlusion to the post-opening mean arterial pressure (%) did not exceed 58% in any patient in the high and moderate risk groups, and were at least 60% in all patients of the minimum risk group. Maintenance of a mean stump pressure of 60% or more of the mean systemic pressure during test occlusion may be a more useful index of a good collateral circulation than the absolute value of mean stump pressure.
残端压力(闭塞后反压)的绝对值能否成为良好侧支循环的有用指标?作者连续监测了24例患者在20分钟球囊试验性闭塞前后及过程中的平均动脉压。然后将残端压力与试验性闭塞20分钟后进行的99m锝-六甲基丙烯胺(99mTc-HMPAO)单光子发射计算机断层扫描(SPECT)结果进行比较。那些甚至不能耐受短暂颈动脉闭塞且在SPECT上显示脑血流量(CBF)不对称减少的患者被分为高风险组和中风险组。闭塞侧CBF无显著变化的患者组成最低风险组。高风险组和中风险组共13例患者中有3例平均残端压力超过50 mmHg,最低风险组11例患者中有2例低于50 mmHg。高风险组和中风险组的任何患者中,初始平均残端压力与闭塞前平均动脉压的比值(%)以及闭塞结束时的最终平均残端压力与开放后平均动脉压的比值(%)均未超过58%,而最低风险组的所有患者该比值至少为60%。在试验性闭塞期间维持平均残端压力为平均体循环压力的60%或更高,可能比平均残端压力的绝对值更能作为良好侧支循环的有用指标。