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同种异体半月板移植

Allograft meniscus transplantation.

作者信息

Kuhn J E, Wojtys E M

机构信息

Division of Sports Medicine, University of Michigan Medical Center, Ann Arbor, USA.

出版信息

Clin Sports Med. 1996 Jul;15(3):537-6.

PMID:8800535
Abstract

At this time, meniscal allograft transplantation remains an investigational procedure with very limited indications. To date, no work has shown that the transplanted meniscus is capable of protecting and, preserving the hyaline cartilage of the knee joint. The technical aspects of the procedure have been established and are reproducible. Furthermore, it is apparent that a systemic rejection phenomenon does not seem to occur, and the transplanted meniscus is capable of healing. MR imaging appears to be the best method of assessing postoperative position of the transplanted meniscus in the knee. If the transplanted meniscus cannot be maintained in an anatomic position during weight bearing, it is unlikely to have any functional role. Questions remain with regard to the best way to preserve and sterilize the meniscus and whether the transplanted allograft meniscus is capable of assuming the multifaceted role of the normal meniscus in the knee. As more work is conducted, these questions will be answered, and a better understanding of the efficacy of this novel technique will be achieved.

摘要

目前,同种异体半月板移植仍是一种研究性手术,适应证非常有限。迄今为止,尚无研究表明移植的半月板能够保护并保存膝关节的透明软骨。该手术的技术环节已经确立且可重复。此外,显然似乎不会出现全身性排斥现象,移植的半月板能够愈合。磁共振成像似乎是评估移植半月板在膝关节术后位置的最佳方法。如果在负重过程中移植的半月板无法维持在解剖位置,那么它不太可能发挥任何功能作用。关于半月板的最佳保存和消毒方法以及移植的同种异体半月板是否能够承担正常半月板在膝关节中的多方面作用,仍存在疑问。随着更多研究的开展,这些问题将得到解答,并且将对这项新技术的疗效有更深入的了解。

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