Kazui T, Kimura N, Komatsu S
Second Department of Surgery, Sapporo Medical University School of Medicine, Japan.
Eur J Cardiothorac Surg. 1995;9(9):491-5. doi: 10.1016/s1010-7940(95)80048-4.
Hundred consecutive patients were operated on for aortic arch aneurysms between January 1986 and October 1993. All operations were performed with the aid of extracorporeal circulation, blood cardioplegia for myocardial protection, and selective cerebral perfusion (SCP) for protection of cerebral ischemia during aortic arch repair. Forty-four patients (44%) had an emergency operation because of frank or impending rupture of aneurysms or acute aortic dissection. Eighty-three patients (83%) underwent total arch replacement, and 54 had concomitant procedures including aortic valve resuspension, aortic valve replacement (AVR), composite graft replacement and coronary artery bypass grafting (CABG). The overall early (30-day) mortality rate was 16%. Multivariate analysis revealed, as significant risk factors, preoperative cardiopulmonary resuscitation, renal-mesenteric ischemia due to acute dissection, previous ascending aorta/arch operation and preoperative stroke. Of the 71 (71%) patients who were free of these risk factors, only one (1.4%) died. One patient (1%), who was preoperatively in shock state, had a distinct stroke. The present data suggest that SCP is a useful method for aortic arch aneurysm operation requiring complex repair of the aortic arch.
1986年1月至1993年10月期间,对连续100例主动脉弓动脉瘤患者进行了手术。所有手术均在体外循环、用于心肌保护的血液心脏停搏以及主动脉弓修复期间用于保护脑缺血的选择性脑灌注(SCP)辅助下进行。44例(44%)患者因动脉瘤明显破裂或即将破裂或急性主动脉夹层而进行了急诊手术。83例(83%)患者接受了全弓置换,54例患者进行了包括主动脉瓣悬吊、主动脉瓣置换(AVR)、复合移植物置换和冠状动脉旁路移植术(CABG)在内的同期手术。总体早期(30天)死亡率为16%。多因素分析显示,术前心肺复苏、急性夹层导致的肾肠系膜缺血、既往升主动脉/弓部手术以及术前中风是显著的危险因素。在71例(71%)无这些危险因素的患者中,只有1例(1.4%)死亡。1例(1%)术前处于休克状态的患者发生了明显的中风。目前的数据表明,SCP是一种用于需要对主动脉弓进行复杂修复的主动脉弓动脉瘤手术的有用方法。