Dunsmuir W D, Feneley M, Corry D A, Bryan J, Kirby R S
Department of Urology, St. Bartholomew's Hospital, London, UK.
Br J Urol. 1996 Feb;77(2):192-3. doi: 10.1046/j.1464-410x.1996.08524.x.
To determine the variation in repeated measurements of post-void residual urine volume (PVR), determined by transabdominal ultrasonography (TAUS), within an individual over time (test-retest reliability).
Forty men with symptomatic benign prostatic hyperplasia and awaiting transurethral resection of the prostate were studied over 3 months. Each underwent TAUS to determine both pre- and post-micturition residual volumes on six occasions within the study period.
Although one-third of the patients had approximately constant residual volumes (variation in range < 120 mL), two-thirds had wide intra-individual variations over time (variation in range 150-670 mL). The values were log transformed to give a normal distribution and subjected to analysis of variance; there was a wide variation between and also within individuals. The larger the mean PVR, the larger was the overall variation in time. For those with a mean PVR of < 100 mL, the variation was less marked and these patients showed a more consistent test-retest repeatability.
Although the PVR determined by TAUS may be useful to indicate aspects of bladder dysfunction or outlet obstruction, the wide variation in repeated measurements in the same individual limits its use for any clinical purpose that requires repeated assessment, e.g. in monitoring the response to treatment. There is poor test-retest reliability and PVRs cannot be determined reliably from a single measurement.
通过经腹超声检查(TAUS)确定个体随时间变化的残余尿量(PVR)重复测量值的变化情况(重测信度)。
对40例有症状的良性前列腺增生且等待经尿道前列腺切除术的男性患者进行了为期3个月的研究。每位患者在研究期间接受6次TAUS检查,以确定排尿前后的残余尿量。
虽然三分之一的患者残余尿量大致恒定(变化范围<120 mL),但三分之二的患者随时间存在较大的个体内差异(变化范围150 - 670 mL)。对这些值进行对数转换以使其呈正态分布,并进行方差分析;个体之间以及个体内部均存在较大差异。平均PVR越大,总体随时间的变化就越大。对于平均PVR<100 mL的患者,差异不太明显,这些患者表现出更一致的重测重复性。
虽然通过TAUS测定的PVR可能有助于指示膀胱功能障碍或出口梗阻的某些方面,但同一患者重复测量值的广泛差异限制了其在需要重复评估的任何临床目的中的应用,例如监测治疗反应。重测信度较差,且不能通过单次测量可靠地确定PVR。