Conroy E A, Liranzo M O, McMahon J, Steck W D, Tuthill R J
Department of Dermatology, Cleveland Clinic Foundation, Ohio 44195, USA.
Cutis. 1996 Jun;57(6):425-7.
Antimalarial agents have long been known to cause a variety of pigmentary disturbances. Quinidine, a cincha alkaloid and D-isomer of quinine, is widely used for the treatment of ventricular arrhythmias. A paucity of literature, however, exists concerning quinidine-associated hyperpigmentation. We describe a case of focal ceruloderma we believe to be secondary to quinidine therapy.
长期以来，人们都知道抗疟药会引起多种色素沉着紊乱。奎尼丁是一种金鸡纳生物碱，也是奎宁的D-异构体，广泛用于治疗室性心律失常。然而，关于奎尼丁相关的色素沉着过度的文献却很少。我们描述了一例我们认为是由奎尼丁治疗引起的局灶性青铜色皮肤病病例。
