Oba K, Yanase T, Nomura M, Morohashi K, Takayanagi R, Nawata H
Third Department of Internal Medicine, Graduate School of Medical Science, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Biochem Biophys Res Commun. 1996 Sep 4;226(1):261-7. doi: 10.1006/bbrc.1996.1343.
Ad4BP (or steroidogenic factor 1, SF-1) has been implicated to be an essential transcriptional factor for steroidogenesis as well as for the development of the reproductive axis. We elucidated the structure of the human Ad4BP gene. The gene is about 30 kb long and is split into 7 exons including a non-coding exon 1. The deduced amino acid sequence of the human Ad4BP consists of 461 amino acid residues and was highly homologous to those of other mammalian species.
Ad4BP（或类固醇生成因子1，SF-1）被认为是类固醇生成以及生殖轴发育所必需的转录因子。我们阐明了人类Ad4BP基因的结构。该基因长约30 kb，被分成7个外显子，包括一个非编码外显子1。人类Ad4BP推导的氨基酸序列由461个氨基酸残基组成，与其他哺乳动物物种的氨基酸序列高度同源。
