Garyfallou G T
Department of Emergency Medicine, Medical Center of Delaware, Newark, USA.
Acad Emerg Med. 1996 Feb;3(2):157-60. doi: 10.1111/j.1553-2712.1996.tb03405.x.
Intravesical bacillus Calmette-Guérin (BCG) administration for bladder cancer may lead to BCG dissemination in the compromised host. A case of a 63-year-old man with shock secondary to BCG sepsis is reported. The recognition and treatment of disseminated BCG infection are discussed. In addition to standard therapy for urosepsis, early therapy with steroids and coverage with antitubercular medications should be initiated for patients with this condition. In general, the author recommends that all febrile patients who have received BCG immunotherapy within three years, and who have no obvious source for their fever, have acid-fast bacilli blood cultures done for Mycobacterium bovis, and that these patients be admitted to the hospital for further evaluation.
膀胱内灌注卡介苗（BCG）治疗膀胱癌可能导致卡介苗在免疫功能低下的宿主中播散。本文报告了一例63岁男性因卡介苗败血症继发休克的病例。文中讨论了播散性卡介苗感染的识别与治疗。对于患有这种疾病的患者，除了采用治疗泌尿道感染的标准疗法外，还应尽早开始使用类固醇治疗并使用抗结核药物。一般来说，作者建议所有在三年内接受过卡介苗免疫治疗且发热无明显原因的发热患者，进行牛分枝杆菌的抗酸杆菌血培养，并将这些患者收住入院作进一步评估。
